InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: TAL2

Summary

InnateDB Protein

IDBP-79718.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

TAL2

Protein Name

T-cell acute lymphocytic leukemia 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000334547

InnateDB Gene

IDBG-79714 (TAL2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Note=A chromosomal aberration involving TAL2 may be a cause of some T-cell acute lymphoblastic leukemia (T-ALL). Translocation t(7;9)(q34;q32) with TCRB.

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 7 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	7 [view]
Protein-Protein	7 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003677	DNA binding
GO:0046983	protein dimerization activity

Biological Process

GO:0006351	transcription, DNA-templated
GO:0006355	regulation of transcription, DNA-templated
GO:0009791	post-embryonic development
GO:0021794	thalamus development
GO:0030901	midbrain development
GO:0035264	multicellular organism growth