InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STK19

Summary

InnateDB Protein

IDBP-79808.7

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STK19

Protein Name

serine/threonine kinase 19

Synonyms

D6S60; D6S60E; G11; HLA-RP1; RP1;

Species

Homo sapiens

Ensembl Protein

ENSP00000364480

InnateDB Gene

IDBG-79802 (STK19)

Protein Structure

UniProt Annotation

Function

Seems to be a protein kinase. In vitro it can phosphorylate casein-alpha on serine and threonine residues and histones on serine residues.

Subcellular Localization

Nucleus.

Disease Associations

Tissue Specificity

Monocytes, hepatocytes, epithelial cells, T- and B-lymphocytes.

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 10 experimentally validated interaction(s) in this database.

Experimentally validated
Total	10 [view]
Protein-Protein	8 [view]
Protein-DNA	2 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004674	protein serine/threonine kinase activity
GO:0005524	ATP binding

Biological Process

GO:0006468

protein phosphorylation

Cellular Component

GO:0005634

nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR018865 Serine-threonine protein kinase 19

PFAM

PF10494

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P49842

PhosphoSite

PhosphoSite-

TrEMBL

C9J6S8

UniProt Splice Variant

Entrez Gene

8859

UniGene

Hs.654371

RefSeq

NP_004188

HUGO

HGNC:11398

OMIM

604977

CCDS

CCDS34417

HPRD

07281

IMGT

EMBL

AF019413 AL049547 AL645922 AL662849 AL844853 BX679671 CH471081 CR753822 CR753845 CR759782 L26260 L26261 U24578 X77386 X77474 X77489 X77490 X77491

GenPept

AAA20120 AAA20122 AAA99716 AAB67976 CAA54565 CAA54622 CAA54623 CAB89303 CAB89304 CAI17468 CAI17470 CAI41868 CAM26056 CAM26057 CAM26064 CAM26065 CAQ07123 CAQ07124 CAQ09282 CAQ09283 CAQ10913 CAQ10914 EAX03566 EAX03567