Version 5.4
Homo sapiens Protein: ACTL7A
Summary
InnateDB Protein IDBP-79881.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol ACTL7A
Protein Name actin-like 7A
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000334300
InnateDB Gene IDBG-79879 (ACTL7A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Cytoplasm, cytoskeleton {ECO:0000250}. Golgi apparatus {ECO:0000250}. Cytoplasm {ECO:0000250}. Nucleus {ECO:0000250}. Note=Detected at the Golgi apparatus during acrosome biogenesis. Detected at the subacrosomal layer in round spermatids. Detected in sperm head and tail (By similarity). {ECO:0000250}.
Disease Associations
Tissue Specificity Strongly expressed in testis. Also expressed in other tissues. {ECO:0000269PubMed:10373328}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.
Experimentally validated
Total 5 [view]
Protein-Protein 3 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005200 structural constituent of cytoskeleton
GO:0005515 protein binding
Biological Process
Cellular Component
GO:0001673 male germ cell nucleus
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005856 cytoskeleton
GO:0031514 motile cilium
GO:0043234 protein complex
Protein Structure and Domains
PDB ID
InterPro IPR004000 Actin-related protein
PFAM PF00022
PRINTS PR00190
PIRSF
SMART SM00268
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y615
PhosphoSite PhosphoSite-Q9Y615
TrEMBL
UniProt Splice Variant
Entrez Gene 10881
UniGene Hs.123530
RefSeq NP_006678
HUGO HGNC:161
OMIM 604303
CCDS CCDS6772
HPRD 11976
IMGT
EMBL AB284520 AF113526 AK314981 AL359692 BC014610 CH471105
GenPept AAD44109 AAH14610 BAF41971 BAG37480 CAI40571 EAW59026

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca