InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MYL1

Summary

InnateDB Protein

IDBP-79943.5

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MYL1

Protein Name

myosin, light chain 1, alkali; skeletal, fast

Synonyms

MLC1F; MLC3F;

Species

Homo sapiens

Ensembl Protein

ENSP00000307280

InnateDB Gene

IDBG-79939 (MYL1)

Protein Structure

UniProt Annotation

Function

Regulatory light chain of myosin. Does not bind calcium.

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0008307	structural constituent of muscle

Biological Process

GO:0006936	muscle contraction
GO:0030049	muscle filament sliding
GO:0060048	cardiac muscle contraction

Cellular Component

GO:0005829	cytosol
GO:0005859	muscle myosin complex
GO:0030016	myofibril
GO:0030017	sarcomere
GO:0043292	contractile fiber

Protein Structure and Domains

PDB ID

InterPro

IPR002048 EF-hand domain

PFAM

PF00036
PF13202
PF13405

PRINTS

PIRSF

SMART

SM00054

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

P05976

PhosphoSite

PhosphoSite-P05976

TrEMBL

Q53SD2

UniProt Splice Variant

Entrez Gene

4632

UniGene

Hs.597319

RefSeq

NP_524144

HUGO

HGNC:7582

OMIM

160780

CCDS

CCDS2390

HPRD

01180

IMGT

EMBL

AC021150 AC097525 AK311892 AK311942 BC005318 CH471063 CR456869 J05026 M20642 M20643 X05450 X05451

GenPept

AAA59854 AAA59855 AAA66960 AAH05318 AAY14720 AAY24177 BAG34833 BAG34883 CAA29020 CAB42646 CAG33150 EAW70483 EAW70484