InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: ERBB4

Summary

InnateDB Protein

IDBP-79996.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

ERBB4

Protein Name

v-erb-a erythroblastic leukemia viral oncogene homolog 4 (avian)

Synonyms

ALS19; HER4; p180erbB4;

Species

Homo sapiens

Ensembl Protein

ENSP00000260943

InnateDB Gene

IDBG-79992 (ERBB4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 82 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	82 [view]
Protein-Protein	81 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004714	transmembrane receptor protein tyrosine kinase activity
GO:0005524	ATP binding
GO:0016772	transferase activity, transferring phosphorus-containing groups

Biological Process

GO:0006468	protein phosphorylation
GO:0007169	transmembrane receptor protein tyrosine kinase signaling pathway

Cellular Component

GO:0016020

membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000494 EGF receptor, L domain
IPR006211 Furin-like cysteine-rich domain
IPR006212 Furin-like repeat
IPR009030 Insulin-like growth factor binding protein, N-terminal
IPR011009 Protein kinase-like domain

PFAM

PF01030
PF00757

PRINTS

PIRSF

SMART

SM00261

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite