Homo sapiens Protein: STARD9
Summary
InnateDB Protein IDBP-8047.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol STARD9
Protein Name StAR-related lipid transfer (START) domain containing 9
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000290607
InnateDB Gene IDBG-8045 (STARD9)
Protein Structure
UniProt Annotation
Function Microtubule-dependent motor protein required for spindle pole assembly during mitosis. Required to stabilize the pericentriolar material (PCM). {ECO:0000269PubMed:22153075}.
Subcellular Localization Cytoplasm, cytoskeleton, microtubule organizing center, centrosome, centriole {ECO:0000269PubMed:22153075}. Nucleus {ECO:0000269PubMed:22153075}. Note=Localizes throughout the cytoplasm and nucleus during interphase. Localizes to the daughter centriole during mitosis. Disappears in cytokinesis.
Disease Associations
Tissue Specificity Expressed in the central nervous system, muscle cells (heart and skeletal muscle), pancreas, prostate and lung. {ECO:0000269PubMed:16964419}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003777 microtubule motor activity
GO:0005515 protein binding
GO:0005524 ATP binding
GO:0008017 microtubule binding
GO:0008289 lipid binding
Biological Process
GO:0007018 microtubule-based movement
GO:0008152 metabolic process
GO:0051225 spindle assembly
Cellular Component
GO:0005634 nucleus
GO:0005737 cytoplasm
GO:0005794 Golgi apparatus
GO:0005814 centriole
GO:0005871 kinesin complex
Protein Structure and Domains
PDB ID
InterPro IPR000253 Forkhead-associated (FHA) domain
IPR001752 Kinesin, motor domain
IPR002913 START domain
IPR008984 SMAD/FHA domain
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00498
PF00225
PF01852
PRINTS PR00380
PIRSF
SMART SM00240
SM00129
SM00234
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9P2P6
PhosphoSite PhosphoSite-Q9P2P6
TrEMBL B4DMS6
UniProt Splice Variant
Entrez Gene 57519
UniGene Hs.640660
RefSeq NP_065810
HUGO HGNC:19162
OMIM 614642
CCDS CCDS53935
HPRD
IMGT
EMBL AB037721 AC018362 AC090510 AK122666 AK297603 AL133579 CR627426 CR749416
GenPept BAA92538 BAC85502 BAG59988 CAB63725 CAH10513 CAH18258