InnateDB Protein
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IDBP-8055.7
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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JKAMP
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Protein Name
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JNK1/MAPK8-associated membrane protein
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Synonyms
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000261247
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InnateDB Gene
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IDBG-8053 (JKAMP)
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Protein Structure
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Function |
May be a regulator of the duration of MAPK8 activity in response to various stress stimuli. Facilitates degradation of misfolded endoplasmic reticulum (ER) luminal proteins through the recruitment of components of the proteasome and endoplasmic reticulum-associated degradation (ERAD) system (By similarity). {ECO:0000250}.
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Subcellular Localization |
Endoplasmic reticulum membrane {ECO:0000250}; Multi-pass membrane protein {ECO:0000250}.
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Disease Associations |
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Tissue Specificity |
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Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated |
Total |
13
[view]
|
Protein-Protein |
12
[view]
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Protein-DNA |
1
[view]
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Protein-RNA |
0
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DNA-DNA |
0
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RNA-RNA |
0
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DNA-RNA |
0
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Predicted by orthology |
Total |
1 [view]
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Molecular Function |
Accession |
GO Term |
GO:0031625
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ubiquitin protein ligase binding
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Biological Process |
GO:0006986
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response to unfolded protein
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GO:0030433
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ER-associated ubiquitin-dependent protein catabolic process
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Cellular Component |
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PDB ID |
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InterPro |
IPR008485
Protein of unknown function DUF766
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PFAM |
PF05571
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PRINTS |
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PIRSF |
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SMART |
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TIGRFAMs |
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Modification |
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SwissProt |
Q9P055
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PhosphoSite |
PhosphoSite-Q9P055
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TrEMBL |
G3V372
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UniProt Splice Variant |
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Entrez Gene |
51528
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UniGene |
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RefSeq |
NP_057559
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HUGO |
HGNC:20184
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OMIM |
611176
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CCDS |
CCDS45116
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HPRD |
12623
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IMGT |
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EMBL |
AF151047
AF161445
AF212245
AF529304
AK021683
AK027591
AK298209
AL121694
AL136696
AL159140
AL162471
BC005198
BC010359
BX161501
CH471061
CR457163
CR533510
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GenPept |
AAF29005
AAF36133
AAG41781
AAH05198
AAH10359
AAP85636
BAB13874
BAB55216
BAG60479
CAB66631
CAD61945
CAG33444
CAG38541
EAW80753
EAW80756
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