Homo sapiens Protein: PECR
Summary
InnateDB Protein IDBP-80572.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PECR
Protein Name peroxisomal trans-2-enoyl-CoA reductase
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000265322
InnateDB Gene IDBG-80570 (PECR)
Protein Structure
UniProt Annotation
Function Participates in chain elongation of fatty acids. Has no 2,4-dienoyl-CoA reductase activity.
Subcellular Localization Peroxisome {ECO:0000269PubMed:11669066}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0016491 oxidoreductase activity
GO:0019166 trans-2-enoyl-CoA reductase (NADPH) activity
Biological Process
GO:0006633 fatty acid biosynthetic process
GO:0008152 metabolic process
GO:0033306 phytol metabolic process
GO:0055114 oxidation-reduction process
Cellular Component
GO:0005739 mitochondrion
GO:0005777 peroxisome
GO:0005778 peroxisomal membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR002198 Short-chain dehydrogenase/reductase SDR
IPR002347 Glucose/ribitol dehydrogenase
IPR003560 2,3-dihydro-2,3-dihydroxybenzoate dehydrogenase
IPR013968 Polyketide synthase, KR
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal
PFAM PF00106
PF08659
PF03807
PRINTS PR00080
PR00081
PR01397
PIRSF PIRSF000126
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BY49
PhosphoSite PhosphoSite-Q9BY49
TrEMBL
UniProt Splice Variant
Entrez Gene 55825
UniGene Hs.281680
RefSeq NP_060911
HUGO HGNC:18281
OMIM 605843
CCDS CCDS33375
HPRD 09320
IMGT
EMBL AC010686 AF119841 AF212234 AF232009 AJ250303 AK315795 BC002529 CR457145
GenPept AAF69595 AAF69798 AAH02529 AAK14920 AAY14657 BAG38139 CAB89810 CAG33426