Version 5.4
Homo sapiens Protein: GPSM3
Summary
InnateDB Protein IDBP-80595.5
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol GPSM3
Protein Name G-protein signaling modulator 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000364183
InnateDB Gene IDBG-239563 (GPSM3)
Protein Structure
UniProt Annotation
Function Interacts with subunit of G(i) alpha proteins and regulates the activation of G(i) alpha proteins. {ECO:0000269PubMed:14656218, ECO:0000269PubMed:15096500}.
Subcellular Localization Cytoplasm {ECO:0000269PubMed:15096500}.
Disease Associations
Tissue Specificity Expressed in heart, placenta, lung and liver. {ECO:0000269PubMed:15096500}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.
Experimentally validated
Total 4 [view]
Protein-Protein 4 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005092 GDP-dissociation inhibitor activity
GO:0030695 GTPase regulator activity
Biological Process
GO:0008150 biological_process
GO:0008277 regulation of G-protein coupled receptor protein signaling pathway
GO:0050790 regulation of catalytic activity
Cellular Component
GO:0005575 cellular_component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR003109 GoLoco motif
PFAM PF02188
PRINTS
PIRSF
SMART SM00390
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y4H4
PhosphoSite PhosphoSite-Q9Y4H4
TrEMBL A0A024RCP6
UniProt Splice Variant
Entrez Gene 63940
UniGene Hs.520046
RefSeq NP_071390
HUGO HGNC:13945
OMIM
CCDS CCDS34419
HPRD 13605
IMGT
EMBL AF155657 AJ243937 AK313922 AL662830 AL662884 AL845464 BC018724 BX284686 BX927239 CH471081 CR812478 CR933878
GenPept AAF67476 AAH18724 BAG36643 CAB51288 CAI17541 CAI18360 CAI41816 CAM26229 CAQ06601 CAQ09630 CAQ10705 EAX03620 EAX03623

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca