InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SERPINB6

Summary

InnateDB Protein

IDBP-806452.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SERPINB6

Protein Name

serpin peptidase inhibitor, clade B (ovalbumin), member 6

Synonyms

CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3;

Species

Homo sapiens

Ensembl Protein

ENSP00000484343

InnateDB Gene

IDBG-56735 (SERPINB6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004867	serine-type endopeptidase inhibitor activity

Biological Process

GO:0010951	negative regulation of endopeptidase activity
GO:0030162	regulation of proteolysis

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR023796 Serpin domain

PFAM

PF00079

PRINTS

PIRSF

SMART

SM00093

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8IXH2

UniProt Splice Variant

Entrez Gene

5269

UniGene

RefSeq

NP_001284629

HUGO

HGNC:8950

OMIM

173321

CCDS

CCDS75387

HPRD

IMGT

EMBL

AB209563 AF116727 AK314578 AL133351 BC001394 BC098564 BX538343 CH471087 S69272 Z22658

GenPept

AAB30320 AAH01394 AAH98564 AAO15303 BAD92800 BAG37155 CAA80373 CAD98106 CAI23292 EAW55097 EAW55098