InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SERPINB6

Summary

InnateDB Protein

IDBP-806454.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SERPINB6

Protein Name

serpin peptidase inhibitor, clade B (ovalbumin), member 6

Synonyms

CAP; DFNB91; MSTP057; PI-6; PI6; PTI; SPI3;

Species

Homo sapiens

Ensembl Protein

ENSP00000481398

InnateDB Gene

IDBG-56735 (SERPINB6)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.

Experimentally validated
Total	8 [view]
Protein-Protein	7 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002020	protease binding
GO:0004867	serine-type endopeptidase inhibitor activity

Biological Process

GO:0010951	negative regulation of endopeptidase activity
GO:0030162	regulation of proteolysis

Cellular Component

GO:0005615	extracellular space
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0043234	protein complex
GO:0070062	extracellular vesicular exosome

Protein Structure and Domains

PDB ID

InterPro

IPR023796 Serpin domain

PFAM

PF00079

PRINTS

PIRSF

SMART

SM00093

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q8IXH2

UniProt Splice Variant

Entrez Gene

5269

UniGene

RefSeq

NP_001284629

HUGO

HGNC:8950

OMIM

173321

CCDS

CCDS75386

HPRD

IMGT

EMBL

AB209563 AF116727 AK314578 AL133351 BC001394 BC098564 BX538343 CH471087 S69272 Z22658

GenPept

AAB30320 AAH01394 AAH98564 AAO15303 BAD92800 BAG37155 CAA80373 CAD98106 CAI23292 EAW55097 EAW55098 EAW55102 EAW55103