Version 5.4
Homo sapiens Protein: HEBP2
Summary
InnateDB Protein IDBP-806589.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol HEBP2
Protein Name heme binding protein 2
Synonyms C6orf34; C6ORF34B; PP23; SOUL;
Species Homo sapiens
Ensembl Protein ENSP00000475750
InnateDB Gene IDBG-97063 (HEBP2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 3 [view]
Protein-Protein 3 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
GO:0010917 negative regulation of mitochondrial membrane potential
GO:0010940 positive regulation of necrotic cell death
GO:0035794 positive regulation of mitochondrial membrane permeability
Cellular Component
GO:0005737 cytoplasm
GO:0005739 mitochondrion
GO:0070062 extracellular vesicular exosome
Protein Structure and Domains
PDB ID
InterPro IPR006917 SOUL haem-binding protein
IPR011256 Regulatory factor, effector binding domain
PFAM PF04832
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9Y5Z4
PhosphoSite PhosphoSite-Q9Y5Z4
TrEMBL Q05DB4
UniProt Splice Variant
Entrez Gene 23593
UniGene
RefSeq NP_055135
HUGO HGNC:15716
OMIM 605825
CCDS CCDS5191
HPRD
IMGT
EMBL AF117616 AF411610 AL031003 AY427823 BC008205 BC010290 BC016806 BC016807 BC093037
GenPept AAD32099 AAH08205 AAH10290 AAH16806 AAH16807 AAH93037 AAL07394 AAR88624 CAI20539

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca