Version 5.4
Homo sapiens Protein: CYR61
Summary
InnateDB Protein IDBP-806617.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CYR61
Protein Name cysteine-rich, angiogenic inducer, 61
Synonyms CCN1; GIG1; IGFBP10;
Species Homo sapiens
Ensembl Protein ENSP00000479537
InnateDB Gene IDBG-100054 (CYR61)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005520 insulin-like growth factor binding
Biological Process
GO:0001558 regulation of cell growth
Cellular Component
GO:0005576 extracellular region
Protein Structure and Domains
PDB ID
InterPro IPR000867 Insulin-like growth factor-binding protein, IGFBP
IPR000884 Thrombospondin, type 1 repeat
IPR001007 von Willebrand factor, type C
IPR006207 Cystine knot, C-terminal
IPR012395 IGFBP-related, CNN
PFAM PF00219
PF00090
PF00093
PRINTS
PIRSF PIRSF036495
SMART SM00121
SM00209
SM00214
SM00041
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 3491
UniGene
RefSeq
HUGO HGNC:2654
OMIM 602369
CCDS
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca