Version 5.4
Homo sapiens Protein: IQSEC1
Summary
InnateDB Protein IDBP-806833.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IQSEC1
Protein Name IQ motif and Sec7 domain 1
Synonyms ARF-GEP100; ARFGEP100; BRAG2; GEP100;
Species Homo sapiens
Ensembl Protein ENSP00000480301
InnateDB Gene IDBG-19527 (IQSEC1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 13 experimentally validated interaction(s) in this database.
Experimentally validated
Total 13 [view]
Protein-Protein 13 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005086 ARF guanyl-nucleotide exchange factor activity
GO:0005515 protein binding
Biological Process
GO:0032012 regulation of ARF protein signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000048 IQ motif, EF-hand binding site
IPR000904 Sec7 domain
IPR001849 Pleckstrin homology domain
PFAM PF00612
PF01369
PF00169
PRINTS
PIRSF
SMART SM00015
SM00222
SM00233
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 9922
UniGene
RefSeq NP_001127854
HUGO HGNC:29112
OMIM 610166
CCDS CCDS74902
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca