Homo sapiens Protein: PACSIN1
Summary
InnateDB Protein IDBP-807034.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PACSIN1
Protein Name protein kinase C and casein kinase substrate in neurons 1
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000484060
InnateDB Gene IDBG-83573 (PACSIN1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0005543 phospholipid binding
GO:0008092 cytoskeletal protein binding
Biological Process
GO:0007015 actin filament organization
GO:0045806 negative regulation of endocytosis
GO:0048488 synaptic vesicle endocytosis
GO:0048666 neuron development
GO:0048812 neuron projection morphogenesis
GO:0072657 protein localization to membrane
GO:0090002 establishment of protein localization to plasma membrane
GO:0097320 membrane tubulation
GO:1900006 positive regulation of dendrite development
Cellular Component
GO:0005737 cytoplasm
GO:0005829 cytosol
GO:0005886 plasma membrane
GO:0030054 cell junction
GO:0030137 COPI-coated vesicle
GO:0030659 cytoplasmic vesicle membrane
GO:0032587 ruffle membrane
GO:0043679 axon terminus
GO:0045202 synapse
GO:0048471 perinuclear region of cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001060 FCH domain
IPR001452 SH3 domain
IPR011511 Variant SH3 domain
PFAM PF00611
PF00018
PF14604
PF07653
PRINTS PR00452
PIRSF
SMART SM00055
SM00326
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5TZC3
UniProt Splice Variant
Entrez Gene 29993
UniGene
RefSeq NP_065855
HUGO HGNC:8570
OMIM 606512
CCDS CCDS4793
HPRD
IMGT
EMBL AB037800 AF242529 AK289956 AL834211 BC040228 BX255972 CH471081
GenPept AAH40228 AAK29206 BAA92617 BAF82645 CAD38895 EAX03785 EAX03786 EAX03787