Version 5.4
Homo sapiens Protein: FGA
Summary
InnateDB Protein IDBP-807116.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FGA
Protein Name fibrinogen alpha chain
Synonyms Fib2;
Species Homo sapiens
Ensembl Protein ENSP00000478487
InnateDB Gene IDBG-42099 (FGA)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 30 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 30 [view]
Protein-Protein 30 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005102 receptor binding
GO:0030674 protein binding, bridging
Biological Process
GO:0007165 signal transduction
GO:0030168 platelet activation
GO:0051258 protein polymerization
Cellular Component
GO:0005577 fibrinogen complex
Protein Structure and Domains
PDB ID
InterPro IPR012290 Fibrinogen, alpha/beta/gamma chain, coiled coil domain
PFAM PF08702
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q86Z09
UniProt Splice Variant
Entrez Gene 2243
UniGene
RefSeq
HUGO HGNC:3661
OMIM 134820
CCDS
HPRD
IMGT
EMBL AB087996
GenPept BAC55116

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca