Version 5.4
Homo sapiens Protein: TMEM189
Summary
InnateDB Protein IDBP-80724.6
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol TMEM189
Protein Name transmembrane protein 189
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000360715
InnateDB Gene IDBG-408796 (TMEM189)
Protein Structure
UniProt Annotation
Function
Subcellular Localization Endoplasmic reticulum membrane {ECO:0000269PubMed:11076860}; Multi-pass membrane protein {ECO:0000269PubMed:11076860}.
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.
Experimentally validated
Total 14 [view]
Protein-Protein 14 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR019547 Kua-ubiquitin conjugating enzyme hybrid, localisation
PFAM PF10520
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt A5PLL7
PhosphoSite PhosphoSite-A5PLL7
TrEMBL
UniProt Splice Variant
Entrez Gene 387521
UniGene Hs.696710
RefSeq NP_954580
HUGO HGNC:16735
OMIM 610994
CCDS CCDS13428
HPRD 11926
IMGT
EMBL AB044550 AF155120 AK023028 AL034423 BC142966
GenPept AAF08702 AAI42967 BAB14364 BAB18652

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca