InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: SCN7A

Summary

InnateDB Protein

IDBP-807588.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

SCN7A

Protein Name

sodium channel, voltage-gated, type VII, alpha subunit

Synonyms

NaG; Nav2.1; Nav2.2; SCN6A;

Species

Homo sapiens

Ensembl Protein

ENSP00000478562

InnateDB Gene

IDBG-74239 (SCN7A)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005216	ion channel activity
GO:0005248	voltage-gated sodium channel activity

Biological Process

GO:0006811	ion transport
GO:0006814	sodium ion transport
GO:0006936	muscle contraction
GO:0019228	neuronal action potential
GO:0034765	regulation of ion transmembrane transport
GO:0035725	sodium ion transmembrane transport
GO:0055085	transmembrane transport
GO:0086010	membrane depolarization during action potential

Cellular Component

GO:0001518	voltage-gated sodium channel complex
GO:0005886	plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR001696 Voltage gated sodium channel, alpha subunit
IPR005821 Ion transport domain
IPR010526 Sodium ion transport-associated

PFAM

PF00520
PF06512

PRINTS

PR00170

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q16278

UniProt Splice Variant

Entrez Gene

6332

UniGene

RefSeq

HUGO

HGNC:10594

OMIM

182392

CCDS

HPRD

IMGT

EMBL

AC074101 AC092583 M91556 S75992

GenPept

AAA59899 AAD14203