InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PPP1R2

Summary

InnateDB Protein

IDBP-807709.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PPP1R2

Protein Name

protein phosphatase 1, regulatory (inhibitor) subunit 2

Synonyms

IPP-2; IPP2;

Species

Homo sapiens

Ensembl Protein

ENSP00000484580

InnateDB Gene

IDBG-70546 (PPP1R2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 41 experimentally validated interaction(s) in this database.

Experimentally validated
Total	41 [view]
Protein-Protein	40 [view]
Protein-DNA	0
Protein-RNA	1 [view]
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004864	protein phosphatase inhibitor activity
GO:0004865	protein serine/threonine phosphatase inhibitor activity
GO:0005515	protein binding

Biological Process

GO:0005977	glycogen metabolic process
GO:0006091	generation of precursor metabolites and energy
GO:0009966	regulation of signal transduction
GO:0043086	negative regulation of catalytic activity
GO:0043666	regulation of phosphoprotein phosphatase activity

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR007062 Protein phosphatase inhibitor 2 (IPP-2)

PFAM

PF04979

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-P41236

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AJ133812 AY063767 BC007655 U68106 U68107 U68108 U68109 U68110 U68111 X78873 Z29646

GenPept

AAC51206 AAH07655 AAL48322 CAA55475 CAA82754 CAB41680

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca