InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CHRM3

Summary

InnateDB Protein

IDBP-808234.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHRM3

Protein Name

cholinergic receptor, muscarinic 3

Synonyms

EGBRS; HM3;

Species

Homo sapiens

Ensembl Protein

ENSP00000482377

InnateDB Gene

IDBG-107659 (CHRM3)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004435	phosphatidylinositol phospholipase C activity
GO:0004872	receptor activity
GO:0004930	G-protein coupled receptor activity
GO:0005515	protein binding

Biological Process

GO:0006112	energy reserve metabolic process
GO:0006464	cellular protein modification process
GO:0007165	signal transduction
GO:0007186	G-protein coupled receptor signaling pathway
GO:0007399	nervous system development
GO:0008283	cell proliferation
GO:0044281	small molecule metabolic process
GO:0046541	saliva secretion
GO:0050796	regulation of insulin secretion

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016021	integral component of membrane
GO:0016323	basolateral plasma membrane
GO:0030054	cell junction
GO:0045211	postsynaptic membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000276 G protein-coupled receptor, rhodopsin-like
IPR000995 Muscarinic acetylcholine receptor family
IPR001183 Muscarinic acetylcholine receptor M3
IPR017452 GPCR, rhodopsin-like, 7TM
IPR019424 7TM GPCR, olfactory receptor/chemoreceptor Srsx
IPR019430 7TM GPCR, serpentine receptor class x (Srx)

PFAM

PF00001
PF10320
PF10328

PRINTS

PR00237
PR00243
PR00540

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite