InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: PLP1

Summary

InnateDB Protein

IDBP-808306.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

PLP1

Protein Name

proteolipid protein 1

Synonyms

GPM6C; HLD1; MMPL; PLP; PLP/DM20; PMD; SPG2;

Species

Homo sapiens

Ensembl Protein

ENSP00000481006

InnateDB Gene

IDBG-80835 (PLP1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 8 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	8 [view]
Protein-Protein	8 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005198	structural molecule activity
GO:0005515	protein binding
GO:0019911	structural constituent of myelin sheath

Biological Process

GO:0006954	inflammatory response
GO:0007229	integrin-mediated signaling pathway
GO:0007268	synaptic transmission
GO:0008219	cell death
GO:0008366	axon ensheathment
GO:0010001	glial cell differentiation
GO:0010628	positive regulation of gene expression
GO:0014002	astrocyte development
GO:0021762	substantia nigra development
GO:0022010	central nervous system myelination
GO:0042552	myelination
GO:0042759	long-chain fatty acid biosynthetic process
GO:0048469	cell maturation
GO:0061564	axon development