InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MED22

Summary

InnateDB Protein

IDBP-808487.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MED22

Protein Name

mediator complex subunit 22

Synonyms

MED24; surf-5; SURF5;

Species

Homo sapiens

Ensembl Protein

ENSP00000482438

InnateDB Gene

IDBG-91098 (MED22)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	43 [view]
Protein-Protein	43 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0001104	RNA polymerase II transcription cofactor activity
GO:0005515	protein binding

Biological Process

GO:0006357	regulation of transcription from RNA polymerase II promoter
GO:0006366	transcription from RNA polymerase II promoter

Cellular Component

GO:0005737	cytoplasm
GO:0016592	mediator complex

Protein Structure and Domains

PDB ID

InterPro

IPR009332 Mediator complex, subunit Med22

PFAM

PF06179

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

Q5T8T8

UniProt Splice Variant

Entrez Gene

6837

UniGene

RefSeq

HUGO

HGNC:11477

OMIM

185641

CCDS

CCDS6963

HPRD

IMGT

EMBL

AJ224358 AJ224359 AJ224639 AK124518 AK126069 AL158826 BC024225 BC040111 CH471090 X85178

GenPept

AAH24225 AAH40111 BAG54045 BAG54286 CAA11915 CAA11916 CAA12052 CAA12053 CAA59462 CAI12827 CAI12829 CAI12831 EAW88056 EAW88057 EAW88058 EAW88059 EAW88060