InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BIN2

Summary

InnateDB Protein

IDBP-808521.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BIN2

Protein Name

bridging integrator 2

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000483983

InnateDB Gene

IDBG-33347 (BIN2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 5 experimentally validated interaction(s) in this database.

Experimentally validated
Total	5 [view]
Protein-Protein	5 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005515	protein binding
GO:0005543	phospholipid binding

Biological Process

GO:0006911	phagocytosis, engulfment
GO:0060326	cell chemotaxis
GO:0071800	podosome assembly
GO:0097320	membrane tubulation

Cellular Component

GO:0001891	phagocytic cup
GO:0002102	podosome
GO:0005737	cytoplasm
GO:0005938	cell cortex
GO:0030054	cell junction
GO:0042995	cell projection

Protein Structure and Domains

PDB ID

InterPro

IPR003005 Amphiphysin
IPR004148 BAR domain

PFAM

PF03114

PRINTS

PR01251

PIRSF

SMART

SM00721

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

UniProt Splice Variant

Entrez Gene

51411

UniGene

RefSeq

NP_001276938

HUGO

HGNC:1053

OMIM

605936

CCDS

HPRD

IMGT

EMBL

AB032698 AB032710 AC046135 AF146531 AK000783 BC047686

GenPept

AAD54227 AAH47686 BAA88108 BAA88125 BAA91376