InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CHAC1

Summary

InnateDB Protein

IDBP-808549.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CHAC1

Protein Name

ChaC, cation transport regulator homolog 1 (E. coli)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000484644

InnateDB Gene

IDBG-6874 (CHAC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 3 experimentally validated interaction(s) in this database.

Experimentally validated
Total	3 [view]
Protein-Protein	3 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005112	Notch binding
GO:0005515	protein binding

Biological Process

GO:0006986	response to unfolded protein
GO:0007219	Notch signaling pathway
GO:0010955	negative regulation of protein processing
GO:0022008	neurogenesis
GO:0045746	negative regulation of Notch signaling pathway
GO:0070059	intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress

Cellular Component

GO:0005802	trans-Golgi network
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR006840 ChaC-like protein
IPR013024 Butirosin biosynthesis, BtrG-like

PFAM

PF04752

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC020661 AY702027 BC001683 BC001847 BC019625

GenPept

AAH01683 AAH01847 AAH19625 AAW23972

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca