Version 5.4
Homo sapiens Protein: PTPN6
Summary
InnateDB Protein IDBP-808558.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTPN6
Protein Name protein tyrosine phosphatase, non-receptor type 6
Synonyms HCP; HCPH; HPTP1C; PTP-1C; SH-PTP1; SHP-1; SHP-1L; SHP1;
Species Homo sapiens
Ensembl Protein ENSP00000476175
InnateDB Gene IDBG-15719 (PTPN6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 169 experimentally validated interaction(s) in this database.
They are also associated with 20 interaction(s) predicted by orthology.
Experimentally validated
Total 169 [view]
Protein-Protein 161 [view]
Protein-DNA 8 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 20 [view]
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
PFAM PF00017
PF14633
PRINTS PR00401
PIRSF
SMART SM00252
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL U3KQS1
UniProt Splice Variant
Entrez Gene 5777
UniGene
RefSeq
HUGO HGNC:9658
OMIM 176883
CCDS
HPRD
IMGT
EMBL U47924
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca