InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: IP6K1

Summary

InnateDB Protein

IDBP-808568.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

IP6K1

Protein Name

inositol hexakisphosphate kinase 1

Synonyms

IHPK1; PiUS;

Species

Homo sapiens

Ensembl Protein

ENSP00000482032

InnateDB Gene

IDBG-35427 (IP6K1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0000832	inositol hexakisphosphate 5-kinase activity
GO:0005515	protein binding
GO:0005524	ATP binding
GO:0008440	inositol-1,4,5-trisphosphate 3-kinase activity
GO:0052723	inositol hexakisphosphate 1-kinase activity
GO:0052724	inositol hexakisphosphate 3-kinase activity

Biological Process

GO:0043647	inositol phosphate metabolic process
GO:0044281	small molecule metabolic process
GO:0046854	phosphatidylinositol phosphorylation

Cellular Component

GO:0005634	nucleus
GO:0005654	nucleoplasm
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol

Protein Structure and Domains

PDB ID

InterPro

IPR005522 Inositol polyphosphate kinase

PFAM

PF03770

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC099668 AC139451 AC141000 AK289772 AK295689 BC012944 CH471055 D87452

GenPept

AAH12944 BAA13393 BAF82461 BAG58541 EAW65016 EAW65018 EAW65020

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca