Homo sapiens Protein: DGAT1
Summary
InnateDB Protein IDBP-809005.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol DGAT1
Protein Name diacylglycerol O-acyltransferase 1
Synonyms ARAT; ARGP1; DGAT; DIAR7;
Species Homo sapiens
Ensembl Protein ENSP00000482264
InnateDB Gene IDBG-40588 (DGAT1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003846 2-acylglycerol O-acyltransferase activity
GO:0004144 diacylglycerol O-acyltransferase activity
GO:0005515 protein binding
GO:0016746 transferase activity, transferring acyl groups
GO:0016772 transferase activity, transferring phosphorus-containing groups
GO:0050252 retinol O-fatty-acyltransferase activity
Biological Process
GO:0006641 triglyceride metabolic process
GO:0006644 phospholipid metabolic process
GO:0016310 phosphorylation
GO:0019432 triglyceride biosynthetic process
GO:0019915 lipid storage
GO:0034379 very-low-density lipoprotein particle assembly
GO:0035336 long-chain fatty-acyl-CoA metabolic process
GO:0036155 acylglycerol acyl-chain remodeling
GO:0042572 retinol metabolic process
GO:0044255 cellular lipid metabolic process
GO:0044281 small molecule metabolic process
GO:0046339 diacylglycerol metabolic process
GO:0046474 glycerophospholipid biosynthetic process
GO:0055089 fatty acid homeostasis
Cellular Component
GO:0005789 endoplasmic reticulum membrane
GO:0016020 membrane
GO:0016021 integral component of membrane
GO:0043231 intracellular membrane-bounded organelle
Protein Structure and Domains
PDB ID
InterPro IPR004299 Membrane bound O-acyl transferase, MBOAT
IPR008279 PEP-utilising enzyme, mobile domain
PFAM PF03062
PF00391
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q9BRH5
UniProt Splice Variant
Entrez Gene 8694
UniGene
RefSeq NP_036211
HUGO HGNC:2843
OMIM 604900
CCDS CCDS6420
HPRD
IMGT
EMBL AB057815 AF059202 BC006263 BC015762 BC023565 BC150649 CH471162
GenPept AAC63997 AAH06263 AAH15762 AAH23565 AAI50650 BAC66170 EAW82127 EAW82129