Version 5.4
Homo sapiens Protein: SH2D1A
Summary
InnateDB Protein IDBP-809031.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SH2D1A
Protein Name SH2 domain containing 1A
Synonyms DSHP; EBVS; IMD5; LYP; MTCP1; SAP; SAP/SH2D1A; XLP; XLPD; XLPD1;
Species Homo sapiens
Ensembl Protein ENSP00000477094
InnateDB Gene IDBG-85368 (SH2D1A)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 43 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
Experimentally validated
Total 43 [view]
Protein-Protein 43 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 3 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005070 SH3/SH2 adaptor activity
GO:0005515 protein binding
Biological Process
GO:0006968 cellular defense response
GO:0007267 cell-cell signaling
GO:0009967 positive regulation of signal transduction
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR000980 SH2 domain
PFAM PF00017
PF14633
PRINTS PR00401
PIRSF
SMART SM00252
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60880
PhosphoSite PhosphoSite-O60880
TrEMBL
UniProt Splice Variant
Entrez Gene 4068
UniGene
RefSeq
HUGO HGNC:10820
OMIM 300490
CCDS
HPRD
IMGT
EMBL AB586694 AF072930 AF073019 AF100539 AF100540 AF100541 AF100542 AF100543 AK311911 AL022718 AL023657 BC020732 CH471107 CR542031 CR542043
GenPept AAC62630 AAC62631 AAC79712 AAC79713 AAC79714 AAC79715 AAC79716 AAH20732 BAG34852 BAJ19023 CAA18777 CAA19222 CAG46828 CAG46840 EAX11848 EAX11849

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca