Homo sapiens Protein: CASP4
Summary
InnateDB Protein IDBP-809077.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CASP4
Protein Name caspase 4, apoptosis-related cysteine peptidase
Synonyms ICE(rel)II; ICEREL-II; ICH-2; Mih1/TX; TX;
Species Homo sapiens
Ensembl Protein ENSP00000482808
InnateDB Gene IDBG-69557 (CASP4)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 39 experimentally validated interaction(s) in this database.
Experimentally validated
Total 39 [view]
Protein-Protein 39 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0004197 cysteine-type endopeptidase activity
GO:0008234 cysteine-type peptidase activity
Biological Process
GO:0006508 proteolysis
GO:0006915 apoptotic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR001309 Peptidase C14, ICE, catalytic subunit p20
IPR002138 Peptidase C14, caspase non-catalytic subunit p10
IPR011600 Peptidase C14, caspase domain
IPR015917 Peptidase C14A, caspase precursor p45, core
IPR017350 Caspase, interleukin-1 beta convertase-type
PFAM PF00656
PRINTS PR00376
PIRSF PIRSF038001
SMART SM00115
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q7KYX7
UniProt Splice Variant
Entrez Gene 837
UniGene
RefSeq
HUGO HGNC:1505
OMIM 602664
CCDS
HPRD
IMGT
EMBL CH471065 U28977 U28979
GenPept AAC99851 AAC99854 EAW67050