Version 5.4
Homo sapiens Protein: UCK2
Summary
InnateDB Protein IDBP-809683.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol UCK2
Protein Name uridine-cytidine kinase 2
Synonyms TSA903; UK; UMPK;
Species Homo sapiens
Ensembl Protein ENSP00000476327
InnateDB Gene IDBG-104492 (UCK2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 6 [view]
Protein-Protein 6 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004849 uridine kinase activity
GO:0005524 ATP binding
GO:0016301 kinase activity
GO:0019206 nucleoside kinase activity
Biological Process
GO:0006206 pyrimidine nucleobase metabolic process
GO:0008152 metabolic process
GO:0016310 phosphorylation
GO:0043097 pyrimidine nucleoside salvage
GO:0044206 UMP salvage
GO:0044211 CTP salvage
GO:0044281 small molecule metabolic process
GO:0055086 nucleobase-containing small molecule metabolic process
Cellular Component
GO:0005575 cellular_component
GO:0005829 cytosol
Protein Structure and Domains
PDB ID
InterPro IPR000764 Uridine kinase like
IPR006083 Phosphoribulokinase/uridine kinase
IPR027417 P-loop containing nucleoside triphosphate hydrolase
PFAM PF00485
PRINTS PR00988
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9BZX2
PhosphoSite PhosphoSite-Q9BZX2
TrEMBL
UniProt Splice Variant
Entrez Gene 7371
UniGene
RefSeq
HUGO HGNC:12562
OMIM 609329
CCDS
HPRD
IMGT
EMBL AB062451 AF236637 AL358115 AL451074 BC002906 BT006860 CR456857 D78335
GenPept AAH02906 AAK14053 AAP35506 BAA11349 BAB56162 CAG33138 CAH74066 CAI15121

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca