Version 5.4
Homo sapiens Protein: PTEN
Summary
InnateDB Protein IDBP-810073.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PTEN
Protein Name phosphatase and tensin homolog
Synonyms 10q23del; BZS; CWS1; DEC; GLM2; MHAM; MMAC1; PTEN1; TEP1;
Species Homo sapiens
Ensembl Protein ENSP00000483066
InnateDB Gene IDBG-81409 (PTEN)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 139 experimentally validated interaction(s) in this database.
They are also associated with 13 interaction(s) predicted by orthology.
Experimentally validated
Total 139 [view]
Protein-Protein 135 [view]
Protein-DNA 3 [view]
Protein-RNA 0
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 13 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
Biological Process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000008 C2 domain
IPR014020 Tensin phosphatase, C2 domain
PFAM PF00168
PF10409
PRINTS PR00360
PIRSF
SMART SM00239
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL H6WA51
UniProt Splice Variant
Entrez Gene 5728
UniGene
RefSeq
HUGO HGNC:9588
OMIM 601728
CCDS
HPRD
IMGT
EMBL JQ037774 JQ037775 JQ037777 JQ037778
GenPept AEZ67429 AEZ67430 AEZ67432 AEZ67433

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca