InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: STIM1

Summary

InnateDB Protein

IDBP-810321.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

STIM1

Protein Name

stromal interaction molecule 1

Synonyms

D11S4896E; GOK; IMD10; STRMK; TAM; TAM1;

Species

Homo sapiens

Ensembl Protein

ENSP00000478059

InnateDB Gene

IDBG-24705 (STIM1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 27 experimentally validated interaction(s) in this database.

Experimentally validated
Total	27 [view]
Protein-Protein	26 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005246	calcium channel regulator activity
GO:0005515	protein binding
GO:0015279	store-operated calcium channel activity

Biological Process

GO:0002115	store-operated calcium entry
GO:0006812	cation transport
GO:0070588	calcium ion transmembrane transport
GO:2001256	regulation of store-operated calcium entry

Cellular Component

GO:0005783	endoplasmic reticulum
GO:0005886	plasma membrane
GO:0030426	growth cone
GO:0043234	protein complex

Protein Structure and Domains

PDB ID

InterPro

IPR001660 Sterile alpha motif domain
IPR011510 Sterile alpha motif, type 2
IPR013761 Sterile alpha motif/pointed domain

PFAM

PF07647

PRINTS

PIRSF

SMART

SM00454

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-

TrEMBL

G0XQ39

UniProt Splice Variant

Entrez Gene

6786

UniGene

RefSeq

NP_001264890

HUGO

HGNC:11386

OMIM

605921

CCDS

CCDS73247

HPRD

IMGT

EMBL

AC015689 AC087441 AC090587 AC090804 AC107970 HQ317451

GenPept

ADO20317