InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HIC1

Summary

InnateDB Protein

IDBP-810806.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HIC1

Protein Name

hypermethylated in cancer 1

Synonyms

hic-1; ZBTB29; ZNF901;

Species

Homo sapiens

Ensembl Protein

ENSP00000477858

InnateDB Gene

IDBG-16011 (HIC1)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 45 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	45 [view]
Protein-Protein	44 [view]
Protein-DNA	1 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003700	sequence-specific DNA binding transcription factor activity
GO:0005515	protein binding
GO:0046872	metal ion binding

Biological Process

GO:0000122	negative regulation of transcription from RNA polymerase II promoter
GO:0008630	intrinsic apoptotic signaling pathway in response to DNA damage

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000210 BTB/POZ-like
IPR007087 Zinc finger, C2H2
IPR011333 BTB/POZ fold
IPR013069 BTB/POZ
IPR015880 Zinc finger, C2H2-like

PFAM

PF00096
PF00651

PRINTS

PIRSF

SMART

SM00225
SM00355

TIGRFAMs