Version 5.4
Homo sapiens Protein: KCNJ6
Summary
InnateDB Protein IDBP-811023.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol KCNJ6
Protein Name potassium inwardly-rectifying channel, subfamily J, member 6
Synonyms BIR1; GIRK-2; GIRK2; hiGIRK2; KATP-2; KATP2; KCNJ7; KIR3.2;
Species Homo sapiens
Ensembl Protein ENSP00000477437
InnateDB Gene IDBG-3209 (KCNJ6)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 9 experimentally validated interaction(s) in this database.
Experimentally validated
Total 9 [view]
Protein-Protein 9 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005242 inward rectifier potassium channel activity
GO:0005515 protein binding
GO:0015467 G-protein activated inward rectifier potassium channel activity
Biological Process
GO:0006813 potassium ion transport
GO:0007268 synaptic transmission
GO:0034765 regulation of ion transmembrane transport
GO:0071805 potassium ion transmembrane transport
Cellular Component
GO:0005794 Golgi apparatus
GO:0005886 plasma membrane
GO:0008076 voltage-gated potassium channel complex
GO:0016021 integral component of membrane
Protein Structure and Domains
PDB ID
InterPro IPR003275 Potassium channel, inwardly rectifying, Kir3.2
IPR014756 Immunoglobulin E-set
IPR016449 Potassium channel, inwardly rectifying, Kir
PFAM PF01007
PRINTS PR01328
PR01320
PIRSF PIRSF005465
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt P48051
PhosphoSite PhosphoSite-P48051
TrEMBL
UniProt Splice Variant
Entrez Gene 3763
UniGene
RefSeq NP_002231
HUGO HGNC:6267
OMIM 600877
CCDS CCDS42927
HPRD
IMGT
EMBL BC101547 D87327 G02354 L78480 S78684 S78685 U24660 U52153
GenPept AAB02277 AAB07044 AAB34738 AAC50258 AAI01548 BAA13331

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca