Version 5.4
Homo sapiens Protein: SPCS1
Summary
InnateDB Protein IDBP-811163.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SPCS1
Protein Name signal peptidase complex subunit 1 homolog (S. cerevisiae)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000478310
InnateDB Gene IDBG-39619 (SPCS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 1 experimentally validated interaction(s) in this database.
Experimentally validated
Total 1 [view]
Protein-Protein 1 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003674 molecular_function
GO:0005515 protein binding
GO:0008233 peptidase activity
GO:0043022 ribosome binding
Biological Process
GO:0006412 translation
GO:0006465 signal peptide processing
GO:0006508 proteolysis
GO:0006614 SRP-dependent cotranslational protein targeting to membrane
GO:0010467 gene expression
GO:0044267 cellular protein metabolic process
GO:0050796 regulation of insulin secretion
Cellular Component
GO:0005787 signal peptidase complex
GO:0005789 endoplasmic reticulum membrane
GO:0016021 integral component of membrane
GO:0030176 integral component of endoplasmic reticulum membrane
Protein Structure and Domains
PDB ID
InterPro IPR009542 Microsomal signal peptidase 12kDa subunit
PFAM PF06645
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL X6R2S6
UniProt Splice Variant
Entrez Gene 28972
UniGene
RefSeq
HUGO HGNC:23401
OMIM 610358
CCDS CCDS33769
HPRD
IMGT
EMBL AC104446 AF092138 AK027426 BC000884 CH471055 L38852
GenPept AAD40380 AAH00884 AAL31361 BAG51320 EAW65257

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca