InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: GRHPR

Summary

InnateDB Protein

IDBP-811505.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

GRHPR

Protein Name

glyoxylate reductase/hydroxypyruvate reductase

Synonyms

GLXR; GLYD; PH2;

Species

Homo sapiens

Ensembl Protein

ENSP00000475569

InnateDB Gene

IDBG-65625 (GRHPR)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 17 experimentally validated interaction(s) in this database.

Experimentally validated
Total	17 [view]
Protein-Protein	13 [view]
Protein-DNA	4 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0004616	phosphogluconate dehydrogenase (decarboxylating) activity
GO:0016616	oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor
GO:0051287	NAD binding

Biological Process

GO:0006098	pentose-phosphate shunt
GO:0008152	metabolic process
GO:0055114	oxidation-reduction process

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR006115 6-phosphogluconate dehydrogenase, NADP-binding
IPR006139 D-isomer specific 2-hydroxyacid dehydrogenase, catalytic domain
IPR006140 D-isomer specific 2-hydroxyacid dehydrogenase, NAD-binding domain
IPR028939 Pyrroline-5-carboxylate reductase, catalytic, N-terminal

PFAM

PF03446
PF00389
PF02826
PF03807

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

PhosphoSite-