Version 5.4
Homo sapiens Protein: FBXW2
Summary
InnateDB Protein IDBP-811600.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol FBXW2
Protein Name F-box and WD repeat domain containing 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000476369
InnateDB Gene IDBG-83034 (FBXW2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 23 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.
Experimentally validated
Total 23 [view]
Protein-Protein 22 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 2 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004842 ubiquitin-protein transferase activity
GO:0005515 protein binding
Biological Process
GO:0006464 cellular protein modification process
GO:0006508 proteolysis
GO:0016567 protein ubiquitination
Cellular Component
GO:0005737 cytoplasm
Protein Structure and Domains
PDB ID
InterPro IPR001680 WD40 repeat
IPR001810 F-box domain
IPR017986 WD40-repeat-containing domain
IPR020472 G-protein beta WD-40 repeat
PFAM PF00400
PF00646
PF12937
PF13013
PRINTS PR00320
PIRSF
SMART SM00320
SM00256
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q9UKT8
PhosphoSite PhosphoSite-Q9UKT8
TrEMBL Q4VXH1
UniProt Splice Variant
Entrez Gene 26190
UniGene
RefSeq NP_036296
HUGO HGNC:13608
OMIM 609071
CCDS CCDS43872
HPRD
IMGT
EMBL AF129531 AF145024 AF176698 AF193594 AK022484 AK091860 AK300066 AL138836 AL161911 BC018738 BC110334
GenPept AAF04465 AAF13226 AAH18738 AAI10335 AAP97276 AAP97280 BAB14051 BAG52430 BAG61872 CAI95113

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca