InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: CDH4

Summary

InnateDB Protein

IDBP-812168.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

CDH4

Protein Name

cadherin 4, type 1, R-cadherin (retinal)

Synonyms

CAD4; R-CAD; RCAD;

Species

Homo sapiens

Ensembl Protein

ENSP00000484928

InnateDB Gene

IDBG-83735 (CDH4)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 6 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.

Experimentally validated
Total	6 [view]
Protein-Protein	6 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	1 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding

Biological Process

GO:0007155	cell adhesion
GO:0007156	homophilic cell adhesion
GO:0007157	heterophilic cell-cell adhesion
GO:0007411	axon guidance
GO:0034329	cell junction assembly
GO:0034332	adherens junction organization
GO:0045216	cell-cell junction organization
GO:0045773	positive regulation of axon extension

Cellular Component

GO:0005886	plasma membrane
GO:0005887	integral component of plasma membrane
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

IPR000233 Cadherin, cytoplasmic domain
IPR002126 Cadherin
IPR009124 Cadherin/Desmocollin
IPR014868 Cadherin prodomain
IPR015919 Cadherin-like

PFAM

PF01049
PF00028
PF08758

PRINTS

PR00205
PR01820

PIRSF

SMART

SM00112
SM01055

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AK124724 AL079336 AL109911 AL160412 AL162457 AL365229 AL365401 AL391316 AL450463 AL834206 BC101651 BC112150 BX640515 CH471077 L34059

GenPept

AAA35627 AAI01652 AAI12151 BAG54080 CAC26840 CAD38893 CAH73749 CAI16510 CAI19181 EAW75409

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca