Version 5.4
Homo sapiens Protein: IL28B
Summary
InnateDB Protein IDBP-812194.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol IL28B
Protein Name interferon, lambda 3
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000481633
InnateDB Gene IDBG-50088 (IL28B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
Experimentally validated
Total 11 [view]
Protein-Protein 0
Protein-DNA 9 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 2 [view]
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005125 cytokine activity
Biological Process
GO:0007259 JAK-STAT cascade
GO:0045071 negative regulation of viral genome replication
GO:0050778 positive regulation of immune response
GO:0051607 defense response to virus
Cellular Component
GO:0005615 extracellular space
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 282617
UniGene
RefSeq XP_005258822
HUGO HGNC:18365
OMIM 607402
CCDS
HPRD
IMGT
EMBL AC011445 AY129149 AY184374 AY336714 AY336717 BC130314 BC130316
GenPept AAI30315 AAI30317 AAN28264 AAN86127 AAQ01561 AAR24509

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca