InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: AGRN

Summary

InnateDB Protein

IDBP-812255.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

AGRN

Protein Name

agrin

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000484607

InnateDB Gene

IDBG-84350 (AGRN)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 11 experimentally validated interaction(s) in this database.
They are also associated with 4 interaction(s) predicted by orthology.

Experimentally validated
Total	11 [view]
Protein-Protein	11 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	4 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005509	calcium ion binding
GO:0005515	protein binding
GO:0043236	laminin binding

Biological Process

GO:0007213	G-protein coupled acetylcholine receptor signaling pathway
GO:0043113	receptor clustering

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR000082 SEA domain
IPR000742 Epidermal growth factor-like domain
IPR001791 Laminin G domain
IPR001881 EGF-like calcium-binding domain
IPR002049 EGF-like, laminin
IPR002350 Kazal domain
IPR003645 Follistatin-like, N-terminal
IPR003884 Factor I / membrane attack complex
IPR004850 Agrin NtA domain
IPR008985 Concanavalin A-like lectin/glucanases superfamily
IPR008993 Tissue inhibitor of metalloproteinases-like, OB-fold

PFAM