InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: MSH2

Summary

InnateDB Protein

IDBP-812487.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

MSH2

Protein Name

mutS homolog 2

Synonyms

COCA1; FCC1; HNPCC; HNPCC1; LCFS2;

Species

Homo sapiens

Ensembl Protein

ENSP00000483159

InnateDB Gene

IDBG-50900 (MSH2)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 130 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.

Experimentally validated
Total	132 [view]
Protein-Protein	132 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	3 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0005524	ATP binding
GO:0030983	mismatched DNA binding

Biological Process

GO:0006298

mismatch repair

Cellular Component

Protein Structure and Domains

PDB ID

InterPro

IPR007695 DNA mismatch repair protein MutS-like, N-terminal
IPR007696 DNA mismatch repair protein MutS, core
IPR007860 DNA mismatch repair protein MutS, connector domain
IPR007861 DNA mismatch repair protein MutS, clamp

PFAM

PF01624
PF05192
PF05188
PF05190

PRINTS

PIRSF

SMART

SM00533

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite