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InnateDB Protein
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IDBP-812717.1
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Last Modified
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2014-10-13 [Report errors or provide feedback]
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Gene Symbol
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BACE1
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Protein Name
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beta-site APP-cleaving enzyme 1
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Synonyms
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ASP2; BACE; HSPC104;
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Species
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Homo sapiens
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Ensembl Protein
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ENSP00000475171
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InnateDB Gene
|
IDBG-73181 (BACE1)
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Protein Structure
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| Function |
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| Subcellular Localization |
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| Disease Associations |
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| Tissue Specificity |
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| Comments |
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Number of Interactions
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This gene and/or its encoded proteins are associated with 33 experimentally validated interaction(s) in this database.
They are also associated with 3 interaction(s) predicted by orthology.
| Experimentally validated |
| Total |
33
[view]
|
| Protein-Protein |
31
[view]
|
| Protein-DNA |
2
[view]
|
| Protein-RNA |
0
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| DNA-DNA |
0
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| RNA-RNA |
0
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| DNA-RNA |
0
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| Predicted by orthology |
| Total |
3 [view]
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|
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Molecular Function |
| Accession |
GO Term |
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GO:0004190
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aspartic-type endopeptidase activity
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| Biological Process |
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| Cellular Component |
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| PDB ID |
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| InterPro |
IPR001461
Aspartic peptidase
IPR021109
Aspartic peptidase domain
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| PFAM |
PF00026
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| PRINTS |
PR00792
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| PIRSF |
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| SMART |
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| TIGRFAMs |
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| Modification |
|
| SwissProt |
|
| PhosphoSite |
PhosphoSite-
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| TrEMBL |
U3KPS1
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| UniProt Splice Variant |
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| Entrez Gene |
23621
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| UniGene |
|
| RefSeq |
|
| HUGO |
HGNC:933
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| OMIM |
604252
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| CCDS |
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| HPRD |
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| IMGT |
|
| EMBL |
AP000892
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| GenPept |
|
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Version 5.4