Version 5.4
Homo sapiens Protein: PPP1R12B
Summary
InnateDB Protein IDBP-813081.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol PPP1R12B
Protein Name protein phosphatase 1, regulatory subunit 12B
Synonyms MYPT2; PP1bp55;
Species Homo sapiens
Ensembl Protein ENSP00000476755
InnateDB Gene IDBG-105846 (PPP1R12B)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 12 experimentally validated interaction(s) in this database.
Experimentally validated
Total 12 [view]
Protein-Protein 11 [view]
Protein-DNA 1 [view]
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0005515 protein binding
GO:0008047 enzyme activator activity
Biological Process
GO:0000086 G2/M transition of mitotic cell cycle
GO:0000278 mitotic cell cycle
GO:0006937 regulation of muscle contraction
GO:0007165 signal transduction
GO:0043085 positive regulation of catalytic activity
Cellular Component
GO:0005654 nucleoplasm
GO:0005737 cytoplasm
GO:0005886 plasma membrane
GO:0015629 actin cytoskeleton
Protein Structure and Domains
PDB ID
InterPro IPR002110 Ankyrin repeat
IPR017401 Protein phosphatase 1, regulatory subunit 12A/B/C, eukaryote
IPR020683 Ankyrin repeat-containing domain
PFAM PF00023
PF13606
PF11929
PF12796
PRINTS PR01415
PIRSF PIRSF038141
SMART SM00248
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt O60237
PhosphoSite PhosphoSite-O60237
TrEMBL
UniProt Splice Variant
Entrez Gene 4660
UniGene
RefSeq NP_002472
HUGO HGNC:7619
OMIM 603768
CCDS CCDS1426
HPRD
IMGT
EMBL AB003062 AB050641 AB050642 AC099336 AF324888 AF324889 AF324890 AF324891 AF324892 AL356953 AL589762 BC034430 BC110907 BC144699 CH471067
GenPept AAH34430 AAI10908 AAI44700 AAK00336 AAK00337 BAA28376 BAB17610 BAB17611 CAH73374 CAH73375 CAI15934 CAI15935 EAW91418

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca