Version 5.4
Homo sapiens Protein: SIM2
Summary
InnateDB Protein IDBP-813174.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SIM2
Protein Name single-minded family bHLH transcription factor 2
Synonyms bHLHe15; HMC13F06; HMC29C01; SIM;
Species Homo sapiens
Ensembl Protein ENSP00000476273
InnateDB Gene IDBG-3007 (SIM2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 26 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 26 [view]
Protein-Protein 26 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0004871 signal transducer activity
Biological Process
GO:0006355 regulation of transcription, DNA-templated
GO:0007165 signal transduction
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR000014 PAS domain
IPR013767 PAS fold
PFAM PF13188
PF13426
PF00989
PRINTS
PIRSF
SMART SM00091
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL V9GY04
UniProt Splice Variant
Entrez Gene 6493
UniGene
RefSeq
HUGO HGNC:10883
OMIM 600892
CCDS
HPRD
IMGT
EMBL AP000697
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca