Version 5.4
Homo sapiens Protein: CPS1
Summary
InnateDB Protein IDBP-813369.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol CPS1
Protein Name carbamoyl-phosphate synthase 1, mitochondrial
Synonyms CPSASE1; PHN;
Species Homo sapiens
Ensembl Protein ENSP00000480517
InnateDB Gene IDBG-79973 (CPS1)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 29 experimentally validated interaction(s) in this database.
They are also associated with 1 interaction(s) predicted by orthology.
Experimentally validated
Total 29 [view]
Protein-Protein 27 [view]
Protein-DNA 0
Protein-RNA 1 [view]
DNA-DNA 1 [view]
RNA-RNA 0
DNA-RNA 0
Predicted by orthology
Total 1 [view]
Gene Ontology

Molecular Function
Accession GO Term
GO:0003824 catalytic activity
Biological Process
GO:0006543 glutamine catabolic process
GO:0008152 metabolic process
GO:0070409 carbamoyl phosphate biosynthetic process
Cellular Component
Protein Structure and Domains
PDB ID
InterPro IPR002474 Carbamoyl-phosphate synthase, small subunit N-terminal domain
IPR005481 Carbamoyl-phosphate synthase, large subunit, N-terminal
IPR005483 Carbamoyl-phosphate synthase large subunit, CPSase domain
IPR006274 Carbamoyl-phosphate synthase, small subunit
IPR016185 Pre-ATP-grasp domain
IPR017926 Glutamine amidotransferase
IPR029062 Class I glutamine amidotransferase-like
PFAM PF00988
PF00289
PF00117
PRINTS PR00098
PIRSF
SMART SM01097
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL Q5R211
UniProt Splice Variant
Entrez Gene 1373
UniGene
RefSeq
HUGO HGNC:2323
OMIM 608307
CCDS
HPRD
IMGT
EMBL AB180933 AC007970 AC008172
GenPept BAD74204

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca