InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: HIST1H2AC

Summary

InnateDB Protein

IDBP-813428.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

HIST1H2AC

Protein Name

histone cluster 1, H2ac

Synonyms

dJ221C16.4; H2A/l; H2AFL;

Species

Homo sapiens

Ensembl Protein

ENSP00000473534

InnateDB Gene

IDBG-67915 (HIST1H2AC)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 14 experimentally validated interaction(s) in this database.

Experimentally validated
Total	14 [view]
Protein-Protein	7 [view]
Protein-DNA	7 [view]
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003674	molecular_function
GO:0003677	DNA binding
GO:0043565	sequence-specific DNA binding
GO:0046982	protein heterodimerization activity

Biological Process

GO:0006334	nucleosome assembly
GO:0008150	biological_process

Cellular Component

GO:0000786	nucleosome
GO:0005622	intracellular
GO:0005634	nucleus

Protein Structure and Domains

PDB ID

InterPro

IPR002119 Histone H2A
IPR003958 Transcription factor CBF/NF-Y/archaeal histone
IPR007125 Histone core
IPR009072 Histone-fold

PFAM

PF00808
PF00125

PRINTS

PR00620

PIRSF

SMART

SM00414

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

Q93077

PhosphoSite

PhosphoSite-Q93077

TrEMBL

V9GZN0

UniProt Splice Variant

Entrez Gene

8334

UniGene

RefSeq

HUGO

HGNC:4733

OMIM

602794

CCDS

CCDS4585

HPRD

IMGT

EMBL

AK311811 AY131984 CH471087 K01889 U90551 U91328 Z80778

GenPept

AAA35945 AAB53429 AAB82086 AAN59965 BAG34754 CAB02540 EAW55532 EAW55533