Version 5.4
Homo sapiens Protein: SKOR2
Summary
InnateDB Protein IDBP-813630.1
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol SKOR2
Protein Name SKI family transcriptional corepressor 2
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000483333
InnateDB Gene IDBG-228327 (SKOR2)
Protein Structure
UniProt Annotation
Function
Subcellular Localization
Disease Associations
Tissue Specificity
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 2 experimentally validated interaction(s) in this database.
Experimentally validated
Total 2 [view]
Protein-Protein 2 [view]
Protein-DNA 0
Protein-RNA 0
DNA-DNA 0
RNA-RNA 0
DNA-RNA 0
Gene Ontology

Molecular Function
Accession GO Term
GO:0003714 transcription corepressor activity
GO:0042826 histone deacetylase binding
GO:0046332 SMAD binding
Biological Process
GO:0000122 negative regulation of transcription from RNA polymerase II promoter
GO:0021587 cerebellum morphogenesis
GO:0021702 cerebellar Purkinje cell differentiation
GO:0021936 regulation of cerebellar granule cell precursor proliferation
GO:0030514 negative regulation of BMP signaling pathway
GO:0045880 positive regulation of smoothened signaling pathway
GO:0048814 regulation of dendrite morphogenesis
Cellular Component
GO:0005634 nucleus
Protein Structure and Domains
PDB ID
InterPro IPR003380 Transforming protein Ski
IPR009061 DNA binding domain, putative
IPR010919 SAND domain-like
IPR014890 c-SKI SMAD4-binding domain
PFAM PF02437
PF08782
PRINTS
PIRSF
SMART SM01046
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt
PhosphoSite PhosphoSite-
TrEMBL
UniProt Splice Variant
Entrez Gene 652991
UniGene
RefSeq NP_001264992
HUGO HGNC:32695
OMIM
CCDS CCDS74222
HPRD
IMGT
EMBL
GenPept

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca