InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: BCL2L12

Summary

InnateDB Protein

IDBP-813721.1

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

BCL2L12

Protein Name

BCL2-like 12 (proline rich)

Synonyms

Species

Homo sapiens

Ensembl Protein

ENSP00000482218

InnateDB Gene

IDBG-63278 (BCL2L12)

Protein Structure

UniProt Annotation

Function

Subcellular Localization

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 4 experimentally validated interaction(s) in this database.

Experimentally validated
Total	4 [view]
Protein-Protein	4 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	0
RNA-RNA	0
DNA-RNA	0

Gene Ontology

Molecular Function

Accession	GO Term
GO:0002039	p53 binding
GO:0005515	protein binding

Biological Process

GO:0045944	positive regulation of transcription from RNA polymerase II promoter
GO:1902166	negative regulation of intrinsic apoptotic signaling pathway in response to DNA damage by p53 class mediator
GO:1990001	inhibition of cysteine-type endopeptidase activity involved in apoptotic process
GO:2000773	negative regulation of cellular senescence

Cellular Component

GO:0005634	nucleus
GO:0016020	membrane

Protein Structure and Domains

PDB ID

InterPro

PFAM

PRINTS

PIRSF

SMART

TIGRFAMs

Post-translational Modifications

Modification

Cross-References

SwissProt

PhosphoSite

TrEMBL

UniProt Splice Variant

Entrez Gene

UniGene

RefSeq

HUGO

OMIM

CCDS

HPRD

IMGT

EMBL

AC011495 AF289220 BC007724 BC104004 BC104005 BC104006

GenPept

AAG29495 AAG29496 AAH07724 AAI04005 AAI04006 AAI04007

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1)

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca