Version 5.4
Homo sapiens Protein: RESP18
Summary
InnateDB Protein IDBP-81546.7
Last Modified 2014-10-13 [Report errors or provide feedback]
Gene Symbol RESP18
Protein Name regulated endocrine-specific protein 18 homolog (rat)
Synonyms
Species Homo sapiens
Ensembl Protein ENSP00000330269
InnateDB Gene IDBG-81544 (RESP18)
Protein Structure
UniProt Annotation
Function May play an important regulatory role in corticotrophs. {ECO:0000250}.
Subcellular Localization Secreted {ECO:0000250}. Endoplasmic reticulum {ECO:0000250}. Golgi apparatus {ECO:0000250}. Note=Found in the lumen of dense core vesicles (DCV). {ECO:0000250}.
Disease Associations
Tissue Specificity Pancreas. Found in alpha, beta and delta cells in the pancreatic islets. {ECO:0000269PubMed:17951542}.
Comments
Interactions
Number of Interactions This gene and/or its encoded proteins are associated with 0 experimentally validated interaction(s) in this database.
Gene Ontology

Molecular Function
Accession GO Term
Biological Process
GO:0001701 in utero embryonic development
Cellular Component
GO:0005576 extracellular region
GO:0005783 endoplasmic reticulum
GO:0005794 Golgi apparatus
GO:0030141 secretory granule
GO:0043204 perikaryon
GO:0048237 rough endoplasmic reticulum lumen
Protein Structure and Domains
PDB ID
InterPro
PFAM
PRINTS
PIRSF
SMART
TIGRFAMs
Post-translational Modifications
Modification
Cross-References
SwissProt Q5W5W9
PhosphoSite PhosphoSite-Q5W5W9
TrEMBL
UniProt Splice Variant
Entrez Gene 389075
UniGene Hs.290551
RefSeq NP_001007090
HUGO HGNC:33762
OMIM 612721
CCDS CCDS33382
HPRD 17968
IMGT
EMBL AC114803 AF437883 AF439399 DQ227570
GenPept AAQ04480 AAQ04549 ABB13523

If you use InnateDB for your research, please cite the following publication:

Breuer et al., InnateDB: systems biology of innate immunity and beyond - recent updates and continuing curation. Nucl. Acids Res. (2013) 41 (D1) 

InnateDB is being developed jointly by the Brinkman Laboratory (Simon Fraser University, British Columbia, Canada), the Hancock Laboratory (University of British Columbia, Vancouver, British Columbia) and the Lynn EMBL Australia Group (South Australian Health & Medical Research Institute and Flinders University, Adelaide, Australia).

Funding is currently provided by Allergen and EMBL Australia. Previous funding has been provided by Genome Canada, the Foundation for the National Institutes of Health through the Grand Challenges in Global Health initiative and by Teagasc. InnateDB curated interactions are licensed under the Design Science License. All other data is licensed under the terms of the originating database. Contact: innatedb-mail@sfu.ca