InnateDB: Systems Biology of the Innate Immune Response

Homo sapiens Protein: RPL3

Summary

InnateDB Protein

IDBP-8155.6

Last Modified

2014-10-13 [Report errors or provide feedback]

Gene Symbol

RPL3

Protein Name

ribosomal protein L3

Synonyms

ASC-1; L3; TARBP-B;

Species

Homo sapiens

Ensembl Protein

ENSP00000346001

InnateDB Gene

IDBG-8149 (RPL3)

Protein Structure

UniProt Annotation

Function

The L3 protein is a component of the large subunit of cytoplasmic ribosomes.

Subcellular Localization

Nucleus, nucleolus {ECO:0000269PubMed:16963496}. Cytoplasm {ECO:0000269PubMed:16963496}.

Disease Associations

Tissue Specificity

Comments

Interactions

Number of Interactions

This gene and/or its encoded proteins are associated with 115 experimentally validated interaction(s) in this database.
They are also associated with 2 interaction(s) predicted by orthology.

Experimentally validated
Total	115 [view]
Protein-Protein	113 [view]
Protein-DNA	0
Protein-RNA	0
DNA-DNA	2 [view]
RNA-RNA	0
DNA-RNA	0

Predicted by orthology
Total	2 [view]

Gene Ontology

Molecular Function

Accession	GO Term
GO:0003723	RNA binding
GO:0003735	structural constituent of ribosome
GO:0044822	poly(A) RNA binding

Biological Process

GO:0000184	nuclear-transcribed mRNA catabolic process, nonsense-mediated decay
GO:0006412	translation
GO:0006413	translational initiation
GO:0006414	translational elongation
GO:0006415	translational termination
GO:0006614	SRP-dependent cotranslational protein targeting to membrane
GO:0010467	gene expression
GO:0016032	viral process
GO:0016070	RNA metabolic process
GO:0016071	mRNA metabolic process
GO:0019058	viral life cycle
GO:0019083	viral transcription
GO:0044267	cellular protein metabolic process
GO:0071353	cellular response to interleukin-4

Cellular Component

GO:0005622	intracellular
GO:0005634	nucleus
GO:0005730	nucleolus
GO:0005737	cytoplasm
GO:0005829	cytosol
GO:0005840	ribosome
GO:0022625	cytosolic large ribosomal subunit
GO:0070062	extracellular vesicular exosome